翻訳と辞書 Words near each other ・ N-acyl-D-glutamate deacylase ・ N-Acylamides ・ N-Acylethanolamine ・ N-acylethanolamine acid amide hydrolase ・ N-acylglucosamine 2-epimerase ・ N-acylglucosamine-6-phosphate 2-epimerase ・ N-acylhexosamine oxidase ・ N-acylmannosamine 1-dehydrogenase ・ N-acylmannosamine kinase ・ N-acylneuraminate cytidylyltransferase ・ N-acylneuraminate-9-phosphatase ・ N-acylneuraminate-9-phosphate synthase ・ N-Acylphosphatidylethanolamine ・ N-acylsphingosine galactosyltransferase ・ N-alkylglycine oxidase ・ N-alpha-acetyltransferase 10 ・ N-Arachidonoyl dopamine ・ N-Arachidonylglycine ・ N-ary associativity ・ N-ary code ・ N-ary group ・ N-back ・ N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase ・ N-Benzoyl-N'-phenylurea ・ N-benzyloxycarbonylglycine hydrolase ・ N-body choreography ・ N-body problem ・ N-body simulation ・ N-body units ・ N-bomb Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク N-alpha-acetyltransferase 10 ： ウィキペディア英語版 N-alpha-acetyltransferase 10 N-alpha-acetyltransferase 10 (NAA10) also known as NatA catalytic subunit Naa10 and arrest-defective protein 1 homolog A (ARD1A) is an enzyme that in humans is encoded ''NAA10'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8260 )〕 Together with its auxiliary subunit Naa15, Naa10 constitutes the NatA (Nα-acetyltransferase A) complex that specifically catalyzes the transfer of an acetyl group from acetyl-CoA to the N-terminal primary amino group of certain proteins. In higher eukaryotes, 5 other N-acetyltransferase (NAT) complexes, NatB-NatF, have been described that differ both in substrate specificity and subunit composition. == Gene and transcripts == The human ''NAA10'' is located on chromosome Xq28 and is encoded by 8 exons 2 encoding three different isoforms derived from alternate splicing. Additionally, a processed ''NAA10'' gene duplication ''NAA11'' (''ARD2'') has been identified that is expressed in several human cell lines; however, later studies indicate that Naa11 is not expressed in the human cell lines HeLa and HEK293 or in cancerous tissues, and ''NAA11'' transcripts were only detected in testicular and placental tissues. Naa11 has also been found in mouse, where it is mainly expressed in the testis. ''NAA11'' is located on chromosome 4q21.21 in human and 5 E3 in mouse, and only contains two exons. In mouse, ''NAA10'' is located on chromosome X A7.3 and contains 9 exons. Two alternative splicing products of mouse Naa10, mNaa10235 and mNaa10225, were reported in NIH-3T3 and JB6 cells that may have different activities and function in different subcellular compartments. Homologues for Naa10 have been identified in almost all kingdoms of life analyzed, including plants, fungi,〔 amoebozoa,〔 archaeabacteria〔 and protozoa. In eubacteria, 3 Nα-acetyltransferases, RimI, RimJ and RimL, have been identified but according to their low sequence identity with the NATs, it is likely that the RIM proteins do not have a common ancestor and evolved independently. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「N-alpha-acetyltransferase 10」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.